Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year.Īs global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population. NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Both exceeded the NNV in the general population (1840 best case 1196, worst case 3066). The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351 best case 196, worst case 816) or non-cancer surgery (733 best case 407, worst case 1664).

NNVs were more favourable in surgical patients than the general population. Best- and worst-case scenarios were used to describe uncertainty. NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Now greet your caller with Main Krishna Hoon song by setting it up as your Hello Tune on the Wynk Music App for free.Preoperative SARS-CoV-2 vaccination could support safer elective surgery.

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